Tesfaye Kebede legesse, Khalili Korosh, Abebe Habtamu Tamire, Fekadesilasie Henok Moges


Background: The introduction of image-guided biopsy has revolutionized the quality of patient care by avoiding open surgical biopsies and complications associated with it and the use anesthesia. Even though Ethiopian radiological training dates back to more than two decades, interventional radiology is a very recent introduction. This study reports the safety and significance of image guided biopsy on patient care.

Patients and methods: This study was a prospective study carried out to assess the impact and safety of doing image-guided biopsy in a tertiary care teaching Hospital in Addis Ababa, Ethiopia.

Results: A total of 117 patients, their age ranging from 3 to 80years and a mean age of 41 were evaluated; 6.8% of them were children below the age of 10. Around two-thirds of the cases had intra-abdominal indications for biopsy followed by mediastinal pathologies. Ultrasound was used as a guide in about 85% of the cases. Except for one case that developed massive hemoptysis following fine needle aspiration of a middle mediastinal mass and treated conservatively, there was no major complication. A few minor complications, like mild pain and minor hemorrhage, required only close observation.

Conclusion: On the whole, our study indicates that image-guide biopsy improves the existing medical care. Moreover, institutions particularly those providing training in radiology should promote the establishment of interventional radiology for better patient diagnosis and improved planning of subsequent treatment.

Keywords: Safety, Image-guided biopsy


Full Text:



Mehdi G, Maheshwari V, Afzal S, Ansari HA, Ahmad I. Image-guided fine-needle aspiration of retroperitoneal masses: The role of the cytopathologist. Journal of cytology / Indian Academy of Cytologists. 2013 Jan;30(1):36-41. PubMed PMID: 23661939. Pubmed Central PMCID: PMC3643360. Epub 2013/05/11. eng.

Agha-Mohammadi S, RY C. Solitary splenic metastasis: case report and review of the literature. Am J Clin Oncol. 2001;24:306-10.

Cavanna L, Lazzaro A, Vallisa D, Civardi G, Artioli F. Role of image-guided fine-needle aspiration biopsy in the management of patients with splenic metastasis. World journal of surgical oncology. 2007;5:13. PubMed PMID: 17274814. Pubmed Central PMCID: PMC1800304. Epub 2007/02/06. eng.

McInnes MD, Kielar AZ, Macdonald DB. Percutaneous image-guided biopsy of the spleen: systematic review and meta-analysis of the complication rate and diagnostic accuracy. Radiology. 2011 Sep;260(3):699-708. PubMed PMID: 21693659.

El-Sharkawi D, Ramsay A, Cwynarski K, et al. Clinico-pathologic characteristics of patients with hepatic lymphoma diagnosed using image-guided liver biopsy techniques. Leukemia & lymphoma. 2011 Nov;52(11):2130-4. PubMed PMID: 21702647.

Welch TJ, Sheedy PF, 2nd, Johnson CD, Johnson CM, Stephens DH. CT-guided biopsy: prospective analysis of 1,000 procedures. Radiology. 1989 May;171(2):493-6. PubMed PMID: 2704815. Epub 1989/05/01. eng.

Somers JM, Lomas DJ, Hacking JC, Coleman N, Broadbent VA, Dixon AK. Radiologically-guided cutting needle biopsy for suspected malignancy in childhood. Clinical radiology. 1993 Oct;48(4):236-40. PubMed PMID: 8242998. Epub 1993/10/01. eng.

Memel DS, Dodd GD, 3rd, Esola CC. Efficacy of sonography as a guidance technique for biopsy of abdominal, pelvic, and retroperitoneal lymph nodes. AJR American journal of roentgenology. 1996 Oct;167(4):957-62. PubMed PMID: 8819394. Epub 1996/10/01. eng.

Khankan AA, Al-Muaikeel M. Image-guided percutaneous transthoracic biopsy in lung cancer--emphasis on CT-guided technique. Journal of infection and public health. 2012 Dec;5 Suppl 1:S22-30. PubMed PMID: 23244183.

Fisher AJ, Paulson EK, Sheafor DH, Simmons CM, Nelson RC. Small lymph nodes of the abdomen, pelvis, and retroperitoneum: usefulness of sonographically guided biopsy. Radiology. 1997 Oct;205(1):185-90. PubMed PMID: 9314983. Epub 1997/10/07. eng.

Howlett DC, Drinkwater KJ, Lawrence D, Barter S, Nicholson T. Findings of the UK national audit evaluating image-guided or image-assisted liver biopsy. Part I. Procedural aspects, diagnostic adequacy, and accuracy. Radiology. 2012 Dec;265(3):819-31. PubMed PMID: 23175545.

Hardman RL, Perrich KD, Silas AM. Single-institution results of image-guided nonplugged percutaneous versus transjugular liver biopsy. Cardiovascular and interventional radiology. 2011 Apr;34(2):369-75. PubMed PMID: 20963589.

Howlett DC, Drinkwater KJ, Lawrence D, Barter S, Nicholson T. Findings of the UK national audit evaluating image-guided or image-assisted liver biopsy. Part II. Minor and major complications and procedure-related mortality. Radiology. 2013 Jan;266(1):226-35. PubMed PMID: 23143026.

Silverman SG, Lee BY, Mueller PR, Cibas ES, Seltzer SE. Impact of positive findings at image-guided biopsy of lymphoma on patient care: evaluation of clinical history, needle size, and pathologic findings on biopsy performance. Radiology. 1994 Mar;190(3):759-64. PubMed PMID: 8115624. Epub 1994/03/01. eng.

Rubens DJ, Strang JG, Fultz PJ, Gottlieb RH. Sonographic guidance of mediastinal biopsy: an effective alternative to CT guidance. AJR American journal of roentgenology. 1997 Dec;169(6):1605-10. PubMed PMID: 9393174. Epub 1997/12/11. eng.

Gong Y, Sneige N, Guo M, Hicks M E, A. MC. Transthoracic fine-needle aspiration vs concurrent core needle biopsy in diagnosis of intrathoracic lesions: a retrospective comparison of diagnostic accuracy. Am J Clin Pathol 2006;125(3):438-44.


  • There are currently no refbacks.

Comments on this article

View all comments

Kirkos Sub-City, Woreda 05
Roosevelt street, Infront of Africa Union main gate
Tel: +251 115 533742 Fax: +251 115 151005
P.O.Box 2179 Email:
Copyright © Ethiopian Medical Association 2018 All rights Reserved

Powered by OJS & Designed and Hosted by MAKE Enterprise