ACUTE PANCREATITIS IN ADULT ETHIOPIANS: EXPERIENCE FROM ST. PAUL’S MILLENNIUM MEDICAL COLLEGE HOSPITAL, ADDIS ABABA

Girmaye Tamirat, Mahteme Bekele, Reiye Esayas, Mulat Taye, Sahlu Wondimu

Abstract


Background: Acute pancreatitis is a disease of variable severity, and a high index of clinical suspicion supported by relevant laboratory and imaging studies is necessary to make early diagnosis and improve patient outcome. Objective: This study aims to revise the most common presenting symptoms and signs of acute pancreatitis and the diagnostic modalities used in adult Ethiopian patients.

Methods: A cross-sectional descriptive study was conducted among adult patients with acute pancreatitis admitted to St. Paul’s Millennium Medical College Hospital from January 2005 - December 2011. Data on clinical presentation and outcome of illness was collected from medical records using a structured and pretested questionnaire and analyzed using SPSS Version 16.

Results: A total of 40 patients were admitted to the hospital during the study period. Medical records were retrieved for 30 of them. The male to female ratio was 5:1 and the mean age was 40 years. The majority (76.7%) of patients presented within 3 days of onset of illness. Abdominal pain and vomiting were the most common presenting symptoms seen in 86.7% and 60%, respectively. Tachycardia (60%) abdominal distention (73%) and tenderness (80%) were physical findings. Serum amylase level was elevated in all patients, but was highly elevated in 16 (40%). Ultrasound examination showed features of acute pancreatitis in six (31.6%). Acute pancreatitis was diagnosed on clinical evaluation in 18 (60%) of the cases and intra-operatively in 12 (40%). Six (20%) of the cases died and five of them were among those who underwent surgery.

 


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